4IP8

Structure of human serum amyloid A1

Summary for 4IP8

• Entry DOI: 10.2210/pdb4ip8/pdb
• Related: 4IP9
• Descriptor: Serum amyloid A-1 protein, SULFATE ION, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: secondary amyloid, four-helix bundle, main constituent of secondary amyloid, toll like receptor, human serum, protein binding
• Biological source: Homo sapiens (human)
• Cellular location: Secreted : P0DJI8
• Total number of polymer chains: 4
• Total formula weight: 51275.86

Authors

Lu, J.,Sun, P.D. (deposition date: 2013-01-09, release date: 2014-03-26, Last modification date: 2024-02-28)

• Primary citation: Lu, J.,Yu, Y.,Zhu, I.,Cheng, Y.,Sun, P.D.; Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.; Proc.Natl.Acad.Sci.USA, 111:5189-5194, 2014; PubMed: 24706838; DOI: 10.1073/pnas.1322357111

Experimental method

X-RAY DIFFRACTION (2.193 Å)