4IOC

Crystal structure of compound 4f bound to large ribosomal subunit (50S) from Deinococcus radiodurans

Summary for 4IOC

Entry DOI	10.2210/pdb4ioc/pdb
Related	4IO9 4IOA
Descriptor	23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (32 entities in total)
Functional Keywords	ribosome-ribosome inhibitor complex, ribosome/ribosome inhibitor
Biological source	Deinococcus radiodurans More
Total number of polymer chains	30
Total formula weight	1365975.10
Authors	Han, S.,Marr, E.S. (deposition date: 2013-01-07, release date: 2013-03-06, Last modification date: 2013-03-20)
Primary citation	Magee, T.V.,Han, S.,McCurdy, S.P.,Nguyen, T.T.,Granskog, K.,Marr, E.S.,Maguire, B.A.,Huband, M.D.,Chen, J.M.,Subashi, T.A.,Shanmugasundaram, V. Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. Bioorg.Med.Chem.Lett., 23:1727-1731, 2013 Cited by PubMed: 23414806 DOI: 10.1016/j.bmcl.2013.01.067 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.6 Å)

Structure validation