4IMA

The structure of C436M-hLPYK in complex with Citrate/Mn/ATP/Fru-1,6-BP

Summary for 4IMA

Entry DOI	10.2210/pdb4ima/pdb
Descriptor	Pyruvate kinase, MANGANESE (II) ION, CITRATE ANION, ... (7 entities in total)
Functional Keywords	human liver pyruvate kinase, oxidizable cysteine, phosphorylation, phosphoenolpyruvate, pep, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	236930.66
Authors	Zhang, B.,Holyoak, T.,Fenton, A.W.,Tang, Q.L.,Prasannan, C.B.,Deng, J.P. (deposition date: 2013-01-02, release date: 2013-01-23, Last modification date: 2023-09-20)
Primary citation	Holyoak, T.,Zhang, B.,Deng, J.,Tang, Q.,Prasannan, C.B.,Fenton, A.W. Energetic Coupling between an Oxidizable Cysteine and the Phosphorylatable N-Terminus of Human Liver Pyruvate Kinase. Biochemistry, 52:466-476, 2013 Cited by PubMed: 23270483 DOI: 10.1021/bi301341r PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.954 Å)

Structure validation