4ILW

Complex of matrix metalloproteinase-10 catalytic domain (MMP-10cd) with tissue inhibitor of metalloproteinases-2 (TIMP-2)

Summary for 4ILW

Entry DOI	10.2210/pdb4ilw/pdb
Descriptor	Metalloproteinase inhibitor 2, Stromelysin-2, ZINC ION, ... (5 entities in total)
Functional Keywords	metzincin, ob-fold, metalloproteinase, protease inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P16035 Secreted, extracellular space, extracellular matrix (Probable): P09238
Total number of polymer chains	4
Total formula weight	81209.30
Authors	Batra, J.,Soares, A.S.,Radisky, E.S. (deposition date: 2013-01-01, release date: 2013-11-13, Last modification date: 2023-09-20)
Primary citation	Batra, J.,Soares, A.S.,Mehner, C.,Radisky, E.S. Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes. Plos One, 8:e75836-e75836, 2013 Cited by PubMed: 24073280 DOI: 10.1371/journal.pone.0075836 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.103 Å)

Structure validation