4I9O

Crystal Structure of GACKIX L664C Tethered to 1-10

Summary for 4I9O

Entry DOI	10.2210/pdb4i9o/pdb
Descriptor	CREB-binding protein, 1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	kix domain, transcriptional coactivator, transferase
Biological source	Mus musculus (mouse)
Cellular location	Cytoplasm : P45481
Total number of polymer chains	1
Total formula weight	12631.18
Authors	Wang, N.,Meagher, J.L.,Stuckey, J.A.,Mapp, A.K. (deposition date: 2012-12-05, release date: 2013-03-06, Last modification date: 2017-11-15)
Primary citation	Wang, N.,Majmudar, C.Y.,Pomerantz, W.C.,Gagnon, J.K.,Sadowsky, J.D.,Meagher, J.L.,Johnson, T.K.,Stuckey, J.A.,Brooks, C.L.,Wells, J.A.,Mapp, A.K. Ordering a dynamic protein via a small-molecule stabilizer. J.Am.Chem.Soc., 135:3363-3366, 2013 Cited by PubMed: 23384013 DOI: 10.1021/ja3122334 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation