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4I4W

Peptide length determines the outcome of T cell receptor/peptide-MHCI engagement

Summary for 4I4W
Entry DOI10.2210/pdb4i4w/pdb
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Immunogenic peptide, ... (7 entities in total)
Functional Keywordsmhc i fold, antigen presentation, t-cell receptor, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted : P61769
Total number of polymer chains3
Total formula weight46529.72
Authors
Rizkallah, P.J.,Wooldridge, L.,Cole, D.K. (deposition date: 2012-11-28, release date: 2013-01-02, Last modification date: 2015-11-25)
Primary citationEkeruche-Makinde, J.,Miles, J.J.,van den Berg, H.A.,Skowera, A.,Cole, D.K.,Dolton, G.,Schauenburg, A.J.,Tan, M.P.,Pentier, J.M.,Llewellyn-Lacey, S.,Miles, K.M.,Bulek, A.M.,Clement, M.,Williams, T.,Trimby, A.,Bailey, M.,Rizkallah, P.J.,Rossjohn, J.,Peakman, M.,Price, D.A.,Burrows, S.R.,Sewell, A.K.,Wooldridge, L.
Peptide length determines the outcome of TCR/peptide-MHCI engagement.
Blood, 121:1112-1123, 2013
Cited by
PubMed: 23255554
DOI: 10.1182/blood-2012-06-437202
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.77 Å)
Structure validation

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