4I47

Crystal structure of the Ribosome inactivating protein complexed with methylated guanine

Summary for 4I47

• Entry DOI: 10.2210/pdb4i47/pdb
• Related: 3S9Q
• Descriptor: rRNA N-glycosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one, ... (4 entities in total)
• Functional Keywords: ligand binding, hydrolase, ribosome inactivating protein, n7-methylated guanine
• Biological source: Momordica balsamina (Bitter gourd)
• Total number of polymer chains: 1
• Total formula weight: 27683.31

Authors

Yamini, S.,Kushwaha, G.S.,Bhushan, A.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2012-11-27, release date: 2012-12-12, Last modification date: 2023-11-08)

• Primary citation: Kushwaha, G.S.,Yamini, S.,Kumar, M.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P.; First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina.; Proteins, 81:896-905, 2013; PubMed: 23280611; DOI: 10.1002/prot.24248

Experimental method

X-RAY DIFFRACTION (2.65 Å)