4HZS
Crystal structure of Ack1 kinase domain with C-terminal SH3 domain
Summary for 4HZS
Entry DOI | 10.2210/pdb4hzs/pdb |
Related | 4HZR |
Descriptor | Activated CDC42 kinase 1 (1 entity in total) |
Functional Keywords | inactive state, allostery, dimerization, oligomerization, negative regulation, activation, phosphotransfer, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane: Q07912 |
Total number of polymer chains | 4 |
Total formula weight | 155446.11 |
Authors | Gajiwala, K.S. (deposition date: 2012-11-15, release date: 2013-02-06, Last modification date: 2024-02-28) |
Primary citation | Gajiwala, K.S.,Maegley, K.,Ferre, R.,He, Y.A.,Yu, X. Ack1: activation and regulation by allostery. Plos One, 8:e53994-e53994, 2013 Cited by PubMed: 23342057DOI: 10.1371/journal.pone.0053994 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.23 Å) |
Structure validation
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