4HYT

Na,K-ATPase in the E2P state with bound ouabain and Mg2+ in the cation-binding site

Summary for 4HYT

Entry DOI	10.2210/pdb4hyt/pdb
Related	3KDP 3N23
Descriptor	Sodium/potassium-transporting ATPase subunit alpha-1, O-[(S)-({(2R)-2,3-bis[(9Z)-octadec-9-enoyloxy]propyl}oxy)(hydroxy)phosphoryl]-L-serine, O-DODECANYL OCTAETHYLENE GLYCOL, ... (13 entities in total)
Functional Keywords	membrane transporter, hydrolase-membrane protein complex, hydrolase/membrane protein
Biological source	Sus scrofa (pig) More
Total number of polymer chains	6
Total formula weight	320755.17
Authors	Laursen, M.,Yatime, L.,Nissen, P.,Fedosova, N.U. (deposition date: 2012-11-14, release date: 2013-06-26, Last modification date: 2023-09-20)
Primary citation	Laursen, M.,Yatime, L.,Nissen, P.,Fedosova, N.U. Crystal structure of the high-affinity Na+,K+-ATPase-ouabain complex with Mg2+ bound in the cation binding site. Proc.Natl.Acad.Sci.USA, 110:10958-10963, 2013 Cited by PubMed: 23776223 DOI: 10.1073/pnas.1222308110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.404 Å)

Structure validation