4HX3

Crystal structure of Streptomyces caespitosus sermetstatin in complex with S. caespitosus snapalysin

Summary for 4HX3

• Entry DOI: 10.2210/pdb4hx3/pdb
• Related: 4HWX 4HX2
• Descriptor: Extracellular small neutral protease, Neutral proteinase inhibitor ScNPI, ZINC ION, ... (5 entities in total)
• Functional Keywords: streptomyces subtilisin inhibitor fold, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Streptomyces caespitosus; More
• Cellular location: Secreted: P56406
• Total number of polymer chains: 12
• Total formula weight: 159546.28

Authors

Trillo-Muyo, S.,Martinez-Rodriguez, S.,Arolas, J.L.,Gomis-Ruth, F.X. (deposition date: 2012-11-09, release date: 2012-12-05, Last modification date: 2023-09-20)

• Primary citation: Trillo-Muyo, S.,Martinez-Rodriguez, S.,Arolas, J.L.,Gomis-Ruth, F.X.; Mechanism of action of a Janus-faced single-domain protein inhibitor simultaneously targeting two peptidase classes; CHEM SCI, 4:791-797, 2013; DOI: 10.1039/C2SC21712K

Experimental method

X-RAY DIFFRACTION (2.7 Å)