4HV3
Structure of Ricin A chain bound with N-(N-(pterin-7-yl)carbonyl-L-serinyl)-L-tryptophan
Summary for 4HV3
Entry DOI | 10.2210/pdb4hv3/pdb |
Related | 1BR6 1IFT 1PX8 1PX9 1RTC 4HV7 4esi 4huo 4hup |
Descriptor | Ricin, (2S)-2-[[(2S)-2-[(2-azanyl-4-oxidanylidene-1H-pteridin-7-yl)carbonylamino]-3-oxidanyl-propanoyl]amino]-3-(1H-indol-3-yl)propanoic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | ricin, protein-ligand complex, pterin, hydrolase-hydrolase inhibitor complex, toxin, hydrolase, ribosome-inactivating protein, n-glycosidase, hydrolase/hydrolase inhibitor |
Biological source | Ricinus communis (Castor bean) |
Total number of polymer chains | 1 |
Total formula weight | 30852.57 |
Authors | Robertus, J.D.,Manzano, L.A.,Jasheway, K.R.,Monzingo, A.F.,Saito, R.,Pruet, J.M.,Wiget, P.A.,Anslyn, E.V. (deposition date: 2012-11-05, release date: 2012-12-26, Last modification date: 2023-09-20) |
Primary citation | Saito, R.,Pruet, J.M.,Manzano, L.A.,Jasheway, K.,Monzingo, A.F.,Wiget, P.A.,Kamat, I.,Anslyn, E.V.,Robertus, J.D. Peptide-conjugated pterins as inhibitors of ricin toxin A. J.Med.Chem., 56:320-329, 2013 Cited by PubMed: 23214944DOI: 10.1021/jm3016393 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.54 Å) |
Structure validation
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