4HUT

Structure of ATP:co(I)rrinoid adenosyltransferase (CobA) from Salmonella enterica in complex with four and five-coordinate cob(II)alamin and ATP

Summary for 4HUT

• Entry DOI: 10.2210/pdb4hut/pdb
• Related: 1G5R 1G5T 1G64
• Descriptor: Cob(I)yrinic acid a,c-diamide adenosyltransferase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: transferase
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium
• Cellular location: Cytoplasm: P31570
• Total number of polymer chains: 2
• Total formula weight: 46115.92

Authors

Moore, T.C.,Newmister, S.A.,Rayment, I.,Escalante-Semerena, J.C. (deposition date: 2012-11-04, release date: 2013-01-23, Last modification date: 2023-09-20)

• Primary citation: Moore, T.C.,Newmister, S.A.,Rayment, I.,Escalante-Semerena, J.C.; Structural Insights into the Mechanism of Four-Coordinate Cob(II)alamin Formation in the Active Site of the Salmonella enterica ATP:Co(I)rrinoid Adenosyltransferase Enzyme: Critical Role of Residues Phe91 and Trp93.; Biochemistry, 51:9647-9657, 2012; PubMed: 23148601; DOI: 10.1021/bi301378d

Experimental method

X-RAY DIFFRACTION (1.95 Å)