4HUO

Structure of Ricin A chain bound with N-(N-(pterin-7-yl)carbonylglycyl)-L-phenylalanine

Summary for 4HUO

Entry DOI	10.2210/pdb4huo/pdb
Related	1BR6 1IFT 1RTC 3PX8 3PX9 4HV3 4HV7 4esi 4hup
Descriptor	Ricin, N-[(2-amino-4-oxo-1,4-dihydropteridin-7-yl)carbonyl]glycyl-L-phenylalanine (3 entities in total)
Functional Keywords	ricin, protein-ligand complex, pterin, hydrolase-hydrolase inhibitor complex, toxin, hydrolase, ribosome-inactivating protein, n-glycosidase, hydrolase/hydrolase inhibitor
Biological source	Ricinus communis (Castor bean)
Total number of polymer chains	1
Total formula weight	30348.13
Authors	Jasheway, K.R.,Monzingo, A.F.,Saito, R.,Pruet, J.M.,Manzano, L.A.,Wiget, P.A.,Anslyn, E.V.,Robertus, J.D. (deposition date: 2012-11-02, release date: 2012-12-26, Last modification date: 2023-09-20)
Primary citation	Saito, R.,Pruet, J.M.,Manzano, L.A.,Jasheway, K.,Monzingo, A.F.,Wiget, P.A.,Kamat, I.,Anslyn, E.V.,Robertus, J.D. Peptide-conjugated pterins as inhibitors of ricin toxin A. J.Med.Chem., 56:320-329, 2013 Cited by PubMed: 23214944 DOI: 10.1021/jm3016393 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.52 Å)

Structure validation