4HT4

Molecular Basis of Vancomycin Resistance Transfer in Staphylococcus aureus

Summary for 4HT4

• Entry DOI: 10.2210/pdb4ht4/pdb
• Descriptor: Nicking enzyme, DNA (28-MER), NICKEL (II) ION, ... (6 entities in total)
• Functional Keywords: vancomycin resistance plasmid, dna relaxase, s. aureus, conjugative transfer, dna hairpin, hydrolase-dna complex, hydrolase/dna
• Biological source: Staphylococcus aureus
• Total number of polymer chains: 2
• Total formula weight: 32124.60

Authors

Edwards, J.S. (deposition date: 2012-10-31, release date: 2013-01-30, Last modification date: 2017-11-15)

• Primary citation: Edwards, J.S.,Betts, L.,Frazier, M.L.,Pollet, R.M.,Kwong, S.M.,Walton, W.G.,Ballentine, W.K.,Huang, J.J.,Habibi, S.,Del Campo, M.,Meier, J.L.,Dervan, P.B.,Firth, N.,Redinbo, M.R.; Molecular basis of antibiotic multiresistance transfer in Staphylococcus aureus.; Proc.Natl.Acad.Sci.USA, 110:2804-2809, 2013; PubMed: 23359708; DOI: 10.1073/pnas.1219701110

Experimental method

X-RAY DIFFRACTION (2.907 Å)