4HSC

Crystal structure of a cholesterol dependent cytolysin

Summary for 4HSC

Entry DOI	10.2210/pdb4hsc/pdb
Descriptor	Streptolysin O (2 entities in total)
Functional Keywords	cholesterol-dependent cytolysins, membrane insertion, membrane pore, pore-forming toxins, pore-forming toxin, toxin
Biological source	Streptococcus pyogenes
Total number of polymer chains	1
Total formula weight	63720.29
Authors	Feil, S.C.,Parker, M.W. (deposition date: 2012-10-29, release date: 2013-10-30, Last modification date: 2023-09-20)
Primary citation	Feil, S.C.,Ascher, D.B.,Kuiper, M.J.,Tweten, R.K.,Parker, M.W. Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration. J.Mol.Biol., 426:785-792, 2014 Cited by PubMed: 24316049 DOI: 10.1016/j.jmb.2013.11.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation