4HQI

Structure of O6-Benzyl-2'-deoxyguanosine opposite perimidinone-derived synthetic nucleoside in DNA duplex

Summary for 4HQI

• Entry DOI: 10.2210/pdb4hqi/pdb
• Descriptor: Short modified nucleic acids, SPERMINE, STRONTIUM ION, ... (4 entities in total)
• Functional Keywords: b-form dna, o6-benzyl-2'-deoxyguanosine, dper, perimidinone-derived nucleoside, dickerson-drew dodecamer, dna
• Biological source: SYNTHETIC CONSTRUCT
• Total number of polymer chains: 2
• Total formula weight: 7943.17

Authors

Kowal, E.A.,Lad, R.,Pallan, P.S.,Muffly, E.,Wawrzak, Z.,Egli, M.,Sturla, S.J.,Stone, M.P. (deposition date: 2012-10-25, release date: 2013-07-10, Last modification date: 2024-02-28)

• Primary citation: Kowal, E.A.,Lad, R.R.,Pallan, P.S.,Dhummakupt, E.,Wawrzak, Z.,Egli, M.,Sturla, S.J.,Stone, M.P.; Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction.; Nucleic Acids Res., 41:7566-7576, 2013; PubMed: 23748954; DOI: 10.1093/nar/gkt488

Experimental method

X-RAY DIFFRACTION (1.7 Å)