4HPT

Crystal structure of the catalytic subunit of cAMP-dependent protein kinase displaying complete phosphoryl transfer of AMP-PNP onto a substrate peptide

Summary for 4HPT

Entry DOI	10.2210/pdb4hpt/pdb
Related	1ATP 1JBP 1JLU 1L3R 4DFX 4DG0 4DH1 4hpu
Descriptor	cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total)
Functional Keywords	protein kinase, phosphotransferase, regulatory subunits, pki, magnesium, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Mus musculus (mouse) More
Cellular location	Cytoplasm . Isoform 2: Cell projection, cilium, flagellum : P05132
Total number of polymer chains	2
Total formula weight	43491.49
Authors	Bastidas, A.C.,Steichen, J.M.,Wu, J.,Taylor, S.S. (deposition date: 2012-10-24, release date: 2013-03-20, Last modification date: 2017-11-15)
Primary citation	Bastidas, A.C.,Deal, M.S.,Steichen, J.M.,Guo, Y.,Wu, J.,Taylor, S.S. Phosphoryl transfer by protein kinase a is captured in a crystal lattice. J.Am.Chem.Soc., 135:4788-4798, 2013 Cited by PubMed: 23458248 DOI: 10.1021/ja312237q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation