4HNO

High resolution crystal structure of DNA Apurinic/apyrimidinic (AP) endonuclease IV Nfo from Thermatoga maritima

Summary for 4HNO

Entry DOI	10.2210/pdb4hno/pdb
Descriptor	Probable endonuclease 4, ZINC ION, MANGANESE (II) ION, ... (8 entities in total)
Functional Keywords	endonuclease 4, endodeoxyribonuclease iv, endo iv, nfo, metalloprotein, dna damage, dna repair, base excision repair, hydrolase
Biological source	Thermotoga maritima
Total number of polymer chains	1
Total formula weight	33223.72
Authors	Shin, D.S.,Hosfield, D.J.,Arvai, A.S.,Tsutakawa, S.E.,Tainer, J.A. (deposition date: 2012-10-20, release date: 2013-01-23, Last modification date: 2023-09-20)
Primary citation	Tsutakawa, S.E.,Shin, D.S.,Mol, C.D.,Izumi, T.,Arvai, A.S.,Mantha, A.K.,Szczesny, B.,Ivanov, I.N.,Hosfield, D.J.,Maiti, B.,Pique, M.E.,Frankel, K.A.,Hitomi, K.,Cunningham, R.P.,Mitra, S.,Tainer, J.A. Conserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair Enzymes. J.Biol.Chem., 288:8445-8455, 2013 Cited by PubMed: 23355472 DOI: 10.1074/jbc.M112.422774 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.9194 Å)

Structure validation