4HKY

New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and Faropenem

Summary for 4HKY

• Entry DOI: 10.2210/pdb4hky/pdb
• Related: 3RKJ 3RKK 3SBL 3SFP 3SRX 4GYQ 4GYU 4H0D 4HL1 4HL2
• Descriptor: Beta-lactamase NDM-1, (5R,6S)-6-(1-hydroxyethyl)-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (2R)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-5-[(2R)-oxolan-2-yl]-2,3-dihydro-1,3-thiazole-4-carboxylic acid, ... (7 entities in total)
• Functional Keywords: structural genomics, psi-2, protein structure initiative, midwest center for structural genomics, mcsg, structures of mtb proteins conferring susceptibility to known mtb inhibitors, mtbi, alpha-beta-beta-alpha sandwich, hydrolase, psi-biology, hydrolase-antibiotic complex, hydrolase/antibiotic
• Biological source: Klebsiella pneumoniae
• Cellular location: Periplasm : C7C422
• Total number of polymer chains: 2
• Total formula weight: 53613.59

Authors

Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Mire, J.,Sacchettini, J.,Joachimiak, A.,Midwest Center for Structural Genomics (MCSG),Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) (deposition date: 2012-10-15, release date: 2013-01-23, Last modification date: 2023-09-20)

• Primary citation: Kim, Y.,Tesar, C.,Jedrzejczak, R.,Babnigg, J.,Mire, J.,Sacchettini, J.,Joachimiak, A.; New Delhi Metallo-beta-Lactamase-1, Complexed with Cd and Faropenem; To be Published,

Experimental method

X-RAY DIFFRACTION (2.004 Å)