4HHQ

Serum paraoxonase-1 by directed evolution with the H115Q and H134Q mutations

Summary for 4HHQ

Entry DOI	10.2210/pdb4hhq/pdb
Related	1V04 3SRE 3SRG 4HHO
Descriptor	SERUM PARAOXONASE BY DIRECTED EVOLUTION, CALCIUM ION, DODECYL-BETA-D-MALTOSIDE, ... (5 entities in total)
Functional Keywords	6-blades -propeller fold, hydrolase
Biological source	synthetic construct (artificial gene)
Total number of polymer chains	1
Total formula weight	40414.40
Authors	Moshe, B.-D.,Grzegorz, W.,Mikael, E.,Israel, S.,Joel, L.S.,Dan, S.T. (deposition date: 2012-10-10, release date: 2013-03-27, Last modification date: 2018-01-24)
Primary citation	Ben-David, M.,Wieczorek, G.,Elias, M.,Silman, I.,Sussman, J.L.,Tawfik, D.S. Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme. J.Mol.Biol., 425:1028-1038, 2013 Cited by PubMed: 23318950 DOI: 10.1016/j.jmb.2013.01.009 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation