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4HHO

Serum paraoxonase-1 by directed evolution with the H115W mutation

Summary for 4HHO
Entry DOI10.2210/pdb4hho/pdb
Related1V04 3SRE 3SRG 4HHQ
DescriptorSERUM PARAOXONASE BY DIRECTED EVOLUTION, CALCIUM ION, DODECYL-BETA-D-MALTOSIDE, ... (5 entities in total)
Functional Keywords6-blades -propeller fold, hydrolase
Biological sourcesynthetic construct (artificial gene)
Total number of polymer chains1
Total formula weight40402.59
Authors
Moshe, B.-D.,Grzegorz, W.,Mikael, E.,Israel, S.,Joel, L.S.,Dan, S.T. (deposition date: 2012-10-10, release date: 2013-03-27)
Primary citationBen-David, M.,Wieczorek, G.,Elias, M.,Silman, I.,Sussman, J.L.,Tawfik, D.S.
Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme.
J.Mol.Biol., 425:1028-1038, 2013
Cited by
PubMed: 23318950
DOI: 10.1016/j.jmb.2013.01.009
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

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