4HHJ

Dengue serotype 3 RNA-dependent RNA polymerase

Summary for 4HHJ

Entry DOI	10.2210/pdb4hhj/pdb
Related	3VWS
Descriptor	Non-structural protein 5, ZINC ION, HEXAETHYLENE GLYCOL, ... (5 entities in total)
Functional Keywords	rdrp, viral protein, rna-dependent rna polymerase, rna binding, er membrane, transferase
Biological source	Dengue virus 3
Cellular location	Envelope protein E: Virion membrane; Multi- pass membrane protein: Q6DLV0
Total number of polymer chains	1
Total formula weight	74356.38
Authors	Noble, C.G.,Lescar, J. (deposition date: 2012-10-10, release date: 2013-02-27, Last modification date: 2023-11-08)
Primary citation	Noble, C.G.,Lim, S.P.,Chen, Y.L.,Liew, C.W.,Yap, L.,Lescar, J.,Shi, P.-Y. Conformational flexibility of the Dengue virus RNA-dependent RNA polymerase revealed by a complex with an inhibitor J.Virol., 87:5291-5295, 2013 Cited by PubMed: 23408636 DOI: 10.1128/JVI.00045-13 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation