4HE1

Crystal structure of human muscle fructose-1,6-bisphosphatase Q32R mutant complex with fructose-6-phosphate and phosphate

Summary for 4HE1

• Entry DOI: 10.2210/pdb4he1/pdb
• Related: 4HE0 4HE2
• Descriptor: Fructose-1,6-bisphosphatase isozyme 2, 6-O-phosphono-beta-D-fructofuranose, PHOSPHATE ION, ... (6 entities in total)
• Functional Keywords: allosteric enzyme, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cell junction : O00757
• Total number of polymer chains: 1
• Total formula weight: 37135.13

Authors

Shi, R.,Zhu, D.W.,Lin, S.X. (deposition date: 2012-10-03, release date: 2013-10-09, Last modification date: 2023-09-20)

• Primary citation: Shi, R.,Chen, Z.Y.,Zhu, D.W.,Li, C.,Shan, Y.,Xu, G.,Lin, S.X.; Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced AMP Affinity, and Allosteric Signal Transmission Pathway.; Plos One, 8:e71242-e71242, 2013; PubMed: 24086250; DOI: 10.1371/journal.pone.0071242

Experimental method

X-RAY DIFFRACTION (2.23 Å)