4HDO

Crystal structure of the binary Complex of KRIT1 bound to the Rap1 GTPase

Summary for 4HDO

• Entry DOI: 10.2210/pdb4hdo/pdb
• Related: 4HDQ
• Descriptor: Krev interaction trapped protein 1, Ras-related protein Rap-1b, GLYCEROL, ... (6 entities in total)
• Functional Keywords: ra binding motif, ptb fold, gtpase, gtp, rap effector, rap1, heg1, cell-cell junctions, nucleus, signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton: O00522; Cell membrane: P61224
• Total number of polymer chains: 2
• Total formula weight: 57031.45

Authors

Gingras, A.R. (deposition date: 2012-10-02, release date: 2013-07-10, Last modification date: 2023-09-20)

• Primary citation: Gingras, A.R.,Puzon-McLaughlin, W.,Ginsberg, M.H.; The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.; J.Biol.Chem., 288:23639-23649, 2013; PubMed: 23814056; DOI: 10.1074/jbc.M113.462911

Experimental method

X-RAY DIFFRACTION (1.67 Å)