4HC1

Crystal structure of a loop deleted mutant of human MAdCAM-1 D1D2 complexed with Fab 10G3

Summary for 4HC1

• Entry DOI: 10.2210/pdb4hc1/pdb
• Descriptor: Mucosal addressin cell adhesion molecule 1, 10G3 heavy chain, 10G3 light chain, ... (5 entities in total)
• Functional Keywords: immunoglobulin superfamily, rolling and firm adhesion, integrin alpha4beta7, immune system
• Biological source: Homo sapiens (human); More
• Cellular location: Membrane; Single-pass type I membrane protein: Q13477
• Total number of polymer chains: 6
• Total formula weight: 138358.87

Authors

Springer, T.,Yu, Y.,Zhu, J. (deposition date: 2012-09-28, release date: 2013-01-23, Last modification date: 2020-07-29)

• Primary citation: Springer, T.,Yu, Y.,Zhu, J.,Wang, J.-H.,Huang, P.-S.; A Different Fold with an Integrin-Binding Loop Specialized for Flexibility in Mucosal Addressin Cell Adhesion Molecule-1; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.871 Å)