4H7Z

tRNA-guanine transglycosylase Y106F, C158V mutant in complex with guanine

Summary for 4H7Z

• Entry DOI: 10.2210/pdb4h7z/pdb
• Related: 3BL3 3BLD 4E2V 4GCX 4GD0 4H6E
• Descriptor: Queuine tRNA-ribosyltransferase, GUANINE, ZINC ION, ... (5 entities in total)
• Functional Keywords: substrate specificity, bacterial tgt, transferase, queuine, preq1, trna, guanine exchange enzyme
• Biological source: Zymomonas mobilis
• Total number of polymer chains: 1
• Total formula weight: 43398.51

Authors

Biela, I.,Tidten-Luksch, N.,Heine, A.,Reuter, K.,Klebe, G. (deposition date: 2012-09-21, release date: 2012-10-10, Last modification date: 2023-09-20)

• Primary citation: Biela, I.,Tidten-Luksch, N.,Immekus, F.,Glinca, S.,Nguyen, T.X.,Gerber, H.D.,Heine, A.,Klebe, G.,Reuter, K.; Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor.; Plos One, 8:e64240-e64240, 2013; PubMed: 23704982; DOI: 10.1371/journal.pone.0064240

Experimental method

X-RAY DIFFRACTION (1.68 Å)