4H3P

Crystal structure of human ERK2 complexed with a MAPK docking peptide

Summary for 4H3P

• Entry DOI: 10.2210/pdb4h3p/pdb
• Related: 3TEI 4H3Q
• Descriptor: Mitogen-activated protein kinase 1, Ribosomal protein S6 kinase alpha-1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
• Functional Keywords: kinase domain, signaling, linear motif, surface mutation, transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton, spindle (By similarity): P28482; Nucleus: Q15418
• Total number of polymer chains: 4
• Total formula weight: 89230.09

Authors

Gogl, G.,Toeroe, I.,Remenyi, A. (deposition date: 2012-09-14, release date: 2013-02-27, Last modification date: 2023-11-08)

• Primary citation: Gogl, G.,Toeroe, I.,Remenyi, A.; Protein-peptide complex crystallization: a case study on the ERK2 mitogen-activated protein kinase; Acta Crystallogr.,Sect.D, 69:486-489, 2013; PubMed: 23519423; DOI: 10.1107/S0907444912051062

Experimental method

X-RAY DIFFRACTION (2.3 Å)