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4H2F

Human ecto-5'-nucleotidase (CD73): crystal form I (open) in complex with adenosine

Summary for 4H2F
Entry DOI10.2210/pdb4h2f/pdb
Related4H2G 4H2I 4h1y 4h2b
Descriptor5'-nucleotidase, ADENOSINE, ZINC ION, ... (6 entities in total)
Functional Keywordsdimer, hydrolase, phosphatase, extracellular
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Lipid-anchor, GPI-anchor: P21589
Total number of polymer chains1
Total formula weight60854.60
Authors
Straeter, N.,Knapp, K.M.,Zebisch, M.,Pippel, J. (deposition date: 2012-09-12, release date: 2012-11-28, Last modification date: 2014-10-08)
Primary citationKnapp, K.,Zebisch, M.,Pippel, J.,El-Tayeb, A.,Muller, C.E.,Strater, N.
Crystal Structure of the Human Ecto-5'-Nucleotidase (CD73): Insights into the Regulation of Purinergic Signaling.
Structure, 20:2161-2173, 2012
Cited by
PubMed: 23142347
DOI: 10.1016/j.str.2012.10.001
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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