4H1I

Structure of human thymidylate synthase at low salt conditions

Summary for 4H1I

• Entry DOI: 10.2210/pdb4h1i/pdb
• Related: 4GYH
• Descriptor: Thymidylate synthase, SULFATE ION (3 entities in total)
• Functional Keywords: nucleotide metabolism, cancer chemotherapy target, methyl transferase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P04818
• Total number of polymer chains: 4
• Total formula weight: 146198.91

Authors

Brunn, N.,Dibrov, S.,Hermann, T. (deposition date: 2012-09-10, release date: 2012-10-03, Last modification date: 2023-09-13)

• Primary citation: Brunn, N.D.,Dibrov, S.M.,Kao, M.B.,Ghassemian, M.,Hermann, T.; Analysis of mRNA recognition by human thymidylate synthase.; Biosci.Rep., 34:e00168-e00168, 2014; PubMed: 25423174; DOI: 10.1042/BSR20140137

Experimental method

X-RAY DIFFRACTION (3.095 Å)