4GZ5

Crystal structure of human O-GlcNAc Transferase with UDP-GlcNAc

Summary for 4GZ5

Entry DOI	10.2210/pdb4gz5/pdb
Related	4GYW 4GYY 4GZ3 4GZ6
Descriptor	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, SULFATE ION, ... (4 entities in total)
Functional Keywords	ogt, o-glcnac, gt-b, glycosyltransferase, o-glcnacylation, transferase
Biological source	Homo sapiens (human)
Cellular location	Isoform 2: Mitochondrion. Isoform 3: Cytoplasm. Isoform 4: Cytoplasm: O15294
Total number of polymer chains	4
Total formula weight	327864.46
Authors	Lazarus, M.B.,Jiang, J.,Gloster, T.M.,Zandberg, W.F.,Vocadlo, D.J.,Walker, S. (deposition date: 2012-09-06, release date: 2012-10-31, Last modification date: 2024-02-28)
Primary citation	Lazarus, M.B.,Jiang, J.,Gloster, T.M.,Zandberg, W.F.,Whitworth, G.E.,Vocadlo, D.J.,Walker, S. Structural snapshots of the reaction coordinate for O-GlcNAc transferase. Nat.Chem.Biol., 8:966-968, 2012 Cited by PubMed: 23103939 DOI: 10.1038/nchembio.1109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.075 Å)

Structure validation