4GXJ

R283K DNA polymerase beta ternary complex with a templating 8OG and incoming dCTP analog

Summary for 4GXJ

• Entry DOI: 10.2210/pdb4gxj/pdb
• Related: 4GXI 4GXK
• Descriptor: DNA polymerase beta, DNA (5'-D(P*GP*TP*CP*GP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... (8 entities in total)
• Functional Keywords: transferase, lyase/dna polymerase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 48626.58

Authors

Freudenthal, B.D.,Beard, W.A.,Wilson, S.H. (deposition date: 2012-09-04, release date: 2013-01-16, Last modification date: 2023-09-13)

• Primary citation: Freudenthal, B.D.,Beard, W.A.,Wilson, S.H.; DNA polymerase minor groove interactions modulate mutagenic bypass of a templating 8-oxoguanine lesion.; Nucleic Acids Res., 41:1848-1858, 2013; PubMed: 23267011; DOI: 10.1093/nar/gks1276

Experimental method

X-RAY DIFFRACTION (2.2 Å)