4GVI

Crystal structure of mutant (D248N) Salmonella typhimurium family 3 glycoside hydrolase (NagZ) in complex with GlcNAc-1,6-anhMurNAc

Summary for 4GVI

Entry DOI	10.2210/pdb4gvi/pdb
Related	4GVF 4GVG 4GVH
Descriptor	Beta-hexosaminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, ... (5 entities in total)
Functional Keywords	tim-barrel, hydrolase
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium
Cellular location	Cytoplasm (By similarity): Q8ZQ06
Total number of polymer chains	2
Total formula weight	78634.06
Authors	Bacik, J.P.,Mark, B.L. (deposition date: 2012-08-30, release date: 2012-12-19, Last modification date: 2024-02-28)
Primary citation	Bacik, J.P.,Whitworth, G.E.,Stubbs, K.A.,Vocadlo, D.J.,Mark, B.L. Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. Chem.Biol., 19:1471-1482, 2012 Cited by PubMed: 23177201 DOI: 10.1016/j.chembiol.2012.09.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation