4GSK

Crystal structure of an Atg7-Atg10 crosslinked complex

Summary for 4GSK

Entry DOI	10.2210/pdb4gsk/pdb
Related	4GSJ 4GSL
Descriptor	Ubiquitin-like modifier-activating enzyme ATG7, Ubiquitin-like-conjugating enzyme ATG10, ZINC ION (3 entities in total)
Functional Keywords	ubiquitin-like protein activation enzyme, ubiquitin-like protein transfer enzyme, protein transport-ligase complex, protein transport/ligase
Biological source	Saccharomyces cerevisiae (yeast) More
Cellular location	Cytoplasm: P38862 Preautophagosomal structure membrane ; Peripheral membrane protein : Q07879
Total number of polymer chains	4
Total formula weight	179682.46
Authors	Kaiser, S.E.,Mao, K.,Taherbhoy, A.M.,Yu, S.,Olszewski, J.L.,Duda, D.M.,Kurinov, I.,Deng, A.,Fenn, T.D.,Klionsky, D.J.,Schulman, B.A. (deposition date: 2012-08-27, release date: 2012-11-14, Last modification date: 2023-09-13)
Primary citation	Kaiser, S.E.,Mao, K.,Taherbhoy, A.M.,Yu, S.,Olszewski, J.L.,Duda, D.M.,Kurinov, I.,Deng, A.,Fenn, T.D.,Klionsky, D.J.,Schulman, B.A. Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nat.Struct.Mol.Biol., 19:1242-1249, 2012 Cited by PubMed: 23142976 DOI: 10.1038/nsmb.2415 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation