4GRV

The crystal structure of the neurotensin receptor NTS1 in complex with neurotensin (8-13)

Summary for 4GRV

• Entry DOI: 10.2210/pdb4grv/pdb
• Descriptor: Neurotensin receptor type 1, lysozyme chimera, Neurotensin 8-13, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: g-protein coupled receptor, neurotensin receptor, g-protein, signaling protein-agonist complex, signaling protein/agonist
• Biological source: Rattus norvegicus (Rat, Bacteriaphage T4); More
• Cellular location: Cell membrane ; Multi- pass membrane protein : P20789
• Total number of polymer chains: 2
• Total formula weight: 58497.58

Authors

Noinaj, N.,White, J.F.,Shibata, Y.,Love, J.,Kloss, B.,Xu, F.,Gvozdenovic-Jeremic, J.,Shah, P.,Shiloach, J.,Tate, C.G.,Grisshammer, R. (deposition date: 2012-08-27, release date: 2012-10-17, Last modification date: 2023-09-13)

• Primary citation: White, J.F.,Noinaj, N.,Shibata, Y.,Love, J.,Kloss, B.,Xu, F.,Gvozdenovic-Jeremic, J.,Shah, P.,Shiloach, J.,Tate, C.G.,Grisshammer, R.; Structure of the agonist-bound neurotensin receptor.; Nature, 490:508-513, 2012; PubMed: 23051748; DOI: 10.1038/nature11558

Experimental method

X-RAY DIFFRACTION (2.802 Å)