4GRS

Crystal structure of a chimeric DAH7PS

Summary for 4GRS

Entry DOI	10.2210/pdb4grs/pdb
Related	1ZCO 3PG9
Descriptor	Phospho-2-dehydro-3-deoxyheptonate aldolase, 2-dehydro-3-deoxyphosphoheptonate aldolase, TYROSINE (3 entities in total)
Functional Keywords	dahp, dahps, dah7ps, tim barrel, act domain, transferase, allosteric regulation, aromatic biosynthesis, shikimate pathway, transferable allostery
Biological source	Thermotoga maritima More
Total number of polymer chains	4
Total formula weight	149183.51
Authors	Cross, P.J.,Allison, T.M.,Dobson, R.C.J.,Jameson, G.B.,Parker, E.J. (deposition date: 2012-08-26, release date: 2013-02-06, Last modification date: 2023-11-08)
Primary citation	Cross, P.J.,Allison, T.M.,Dobson, R.C.J.,Jameson, G.B.,Parker, E.J. Engineering allosteric control to an unregulated enzyme by transfer of a regulatory domain Proc.Natl.Acad.Sci.USA, 110:2111-2116, 2013 Cited by PubMed: 23345433 DOI: 10.1073/pnas.1217923110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation