4GRG
Crystal structure of IgE complexed with E2_79, an anti-IgE inhibitor
Summary for 4GRG
| Entry DOI | 10.2210/pdb4grg/pdb |
| Descriptor | ANTI-IGE INHIBITOR E2_79, Ig epsilon chain C region (2 entities in total) |
| Functional Keywords | ig-fold, immunity, high/low affinity receptor, immune system-inhibitor complex, immune system/inhibitor |
| Biological source | Escherichia coli More |
| Total number of polymer chains | 4 |
| Total formula weight | 80570.30 |
| Authors | Kim, B.,Jardetzky, T.S. (deposition date: 2012-08-24, release date: 2012-12-12, Last modification date: 2019-07-17) |
| Primary citation | Kim, B.,Eggel, A.,Tarchevskaya, S.S.,Vogel, M.,Prinz, H.,Jardetzky, T.S. Accelerated disassembly of IgE-receptor complexes by a disruptive macromolecular inhibitor. Nature, 491:613-617, 2012 Cited by PubMed: 23103871DOI: 10.1038/nature11546 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (4.24 Å) |
Structure validation
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