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4GOU

Crystal structure of an RGS-RhoGEF from Entamoeba histolytica

Summary for 4GOU
Entry DOI10.2210/pdb4gou/pdb
Related4FID
DescriptorEhRGS-RhoGEF (2 entities in total)
Functional Keywordsrgs domain, dh domain, ph domain, rho guanine nucleotide exchange factor, signaling protein, gtpase accelerating protein, phospholipid binding, heterotrimeric g protein effector, ehgalpha1
Biological sourceEntamoeba histolytica
Total number of polymer chains1
Total formula weight60454.88
Authors
Bosch, D.E.,Kimple, A.J.,Muller, R.E.,Willard, F.S.,Machius, M.,Siderovski, D.P. (deposition date: 2012-08-20, release date: 2013-01-09, Last modification date: 2013-01-30)
Primary citationBosch, D.E.,Kimple, A.J.,Manning, A.J.,Muller, R.E.,Willard, F.S.,Machius, M.,Rogers, S.L.,Siderovski, D.P.
Structural Determinants of RGS-RhoGEF Signaling Critical to Entamoeba histolytica Pathogenesis.
Structure, 21:65-75, 2013
Cited by
PubMed: 23260656
DOI: 10.1016/j.str.2012.11.012
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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