4GGC

Structural Analysis of Human Cdc20 Supports Multi-site Degron Recognition by APC/C

Summary for 4GGC

Entry DOI	10.2210/pdb4ggc/pdb
Related	4GGA
Descriptor	Cell division cycle protein 20 homolog, (4R)-2-METHYLPENTANE-2,4-DIOL (3 entities in total)
Functional Keywords	cell cycle, mitosis, securin, ubiquitination, wd40
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome : Q12834
Total number of polymer chains	1
Total formula weight	35384.81
Authors	Luo, X.,Tian, W.,Tomchick, D.R. (deposition date: 2012-08-06, release date: 2012-11-07, Last modification date: 2024-02-28)
Primary citation	Tian, W.,Li, B.,Warrington, R.,Tomchick, D.R.,Yu, H.,Luo, X. Structural analysis of human Cdc20 supports multisite degron recognition by APC/C. Proc.Natl.Acad.Sci.USA, 109:18419-18424, 2012 Cited by PubMed: 23091007 DOI: 10.1073/pnas.1213438109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation