4GCX

tRNA-guanine transglycosylase Y106F, C158V, V233G mutant in complex with preQ1

Summary for 4GCX

• Entry DOI: 10.2210/pdb4gcx/pdb
• Related: 2NQZ 2NSO 3BL3 3BLD 3BLL 3BLO 4GD0
• Descriptor: Queuine tRNA-ribosyltransferase, 7-DEAZA-7-AMINOMETHYL-GUANINE, ZINC ION, ... (5 entities in total)
• Functional Keywords: substrate specifity, bacterial tgt, transferase, trna, preq1, guanine exchange enzyme
• Biological source: Zymomonas mobilis
• Total number of polymer chains: 1
• Total formula weight: 43476.58

Authors

Schmidt, I.,Tidten-Luksch, N.,Heine, A.,Reuter, K.,Klebe, G. (deposition date: 2012-07-31, release date: 2012-08-29, Last modification date: 2023-09-13)

• Primary citation: Biela, I.,Tidten-Luksch, N.,Immekus, F.,Glinca, S.,Nguyen, T.X.,Gerber, H.D.,Heine, A.,Klebe, G.,Reuter, K.; Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor.; Plos One, 8:e64240-e64240, 2013; PubMed: 23704982; DOI: 10.1371/journal.pone.0064240

Experimental method

X-RAY DIFFRACTION (1.42 Å)