4GCQ

Crystal Structure of E. coli OmpF porin in complex with Carbenicillin

Summary for 4GCQ

• Entry DOI: 10.2210/pdb4gcq/pdb
• Related: 4GCP 4GCS
• Descriptor: Outer membrane protein F, (2S,5R,6R,7R)-6-{[(2R)-2-carboxy-2-phenylacetyl]amino}-7-hydroxy-3,3-dimethyl-4-thia-1-azabicyclo[3.2.0]heptane-2-carbo xylic acid (3 entities in total)
• Functional Keywords: beta-barrel, protein-drug complex, trimer, non-specific channel, carbenicillin binding, outer membrane, membrane protein-antibiotic complex, membrane protein/antibiotic
• Biological source: Escherichia coli
• Cellular location: Cell outer membrane; Multi-pass membrane protein: P02931
• Total number of polymer chains: 2
• Total formula weight: 75103.43

Authors

Ziervogel, B.K.,Roux, B. (deposition date: 2012-07-30, release date: 2012-12-19, Last modification date: 2024-02-28)

• Primary citation: Ziervogel, B.K.,Roux, B.; The Binding of Antibiotics in OmpF Porin.; Structure, 21:76-87, 2013; PubMed: 23201272; DOI: 10.1016/j.str.2012.10.014

Experimental method

X-RAY DIFFRACTION (2.2 Å)