4G63

Crystal structure of cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) in complex with phosphate ions from Legionella pneumophila, Northeast Structural Genomics Consortium Target LgR1

Summary for 4G63

• Entry DOI: 10.2210/pdb4g63/pdb
• Related: 2BDE
• Descriptor: Cytosolic IMP-GMP specific 5'-nucleotidase, PHOSPHATE ION (3 entities in total)
• Functional Keywords: structural genomics, psi-biology, northeast structural genomics consortium, nesg, alpha-beta protein, had-like superfamily, dna binding protein
• Biological source: Legionella pneumophila subsp. pneumophila
• Total number of polymer chains: 1
• Total formula weight: 54926.43

Authors

Forouhar, F.,Abashidze, M.,Seetharaman, J.,Ho, C.K.,Ciccosanti, C.,Mao, L.,Xiao, R.,Acton, T.B.,Montelione, G.T.,Tong, L.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2012-07-18, release date: 2012-10-10, Last modification date: 2023-09-13)

• Primary citation: Srinivasan, B.,Forouhar, F.,Shukla, A.,Sampangi, C.,Kulkarni, S.,Abashidze, M.,Seetharaman, J.,Lew, S.,Mao, L.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Balaram, H.; Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.; Febs J., 281:1613-1628, 2014; PubMed: 24456211; DOI: 10.1111/febs.12727

Experimental method

X-RAY DIFFRACTION (2.7 Å)