4G1W
Crystal structure of JNK1 in complex with JIP1 peptide and 7-Fluoro-3-[4-(2-hydroxy-ethanesulfonyl)-benzyl]-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester
Summary for 4G1W
Entry DOI | 10.2210/pdb4g1w/pdb |
Descriptor | Mitogen-activated protein kinase 8, C-Jun-amino-terminal kinase-interacting protein 1, methyl 7-fluoro-3-{4-[(2-hydroxyethyl)sulfonyl]benzyl}-4-oxo-1-phenyl-1,4-dihydroquinoline-2-carboxylate, ... (4 entities in total) |
Functional Keywords | kinase inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): Q9UQF2 |
Total number of polymer chains | 2 |
Total formula weight | 44429.32 |
Authors | Kuglstatter, A.,Shao, A. (deposition date: 2012-07-11, release date: 2013-07-17, Last modification date: 2023-09-13) |
Primary citation | Gong, L.,Tan, Y.-C.,Boice, G.,Abbot, S. Crystal structure of JNK1 in complex with JIP1 peptide and inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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