4FZH

Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence

Summary for 4FZH

Entry DOI	10.2210/pdb4fzh/pdb
Descriptor	Hemagglutinin-neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	hydrolase
Biological source	Newcastle disease virus (NDV)
Cellular location	Virion membrane; Single-pass type II membrane protein (Potential): P12558
Total number of polymer chains	4
Total formula weight	239375.65
Authors	Yuan, P.,Paterson, R.G.,Leser, G.P.,Lamb, R.A.,Jardetzky, T.S. (deposition date: 2012-07-06, release date: 2012-09-05, Last modification date: 2023-09-13)
Primary citation	Yuan, P.,Paterson, R.G.,Leser, G.P.,Lamb, R.A.,Jardetzky, T.S. Structure of the ulster strain newcastle disease virus hemagglutinin-neuraminidase reveals auto-inhibitory interactions associated with low virulence. Plos Pathog., 8:e1002855-e1002855, 2012 Cited by PubMed: 22912577 DOI: 10.1371/journal.ppat.1002855 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5008 Å)

Structure validation