4FXD

Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA

Summary for 4FXD

• Entry DOI: 10.2210/pdb4fxd/pdb
• Related: 4B08 4FVM 4FYD
• Descriptor: DNA polymerase alpha catalytic subunit A, DNA (5'-D(*TP*TP*TP*TP*CP*GP*CP*TP*GP*CP*CP*CP*GP*CP*CP*T)-3'), RNA (5'-R(*AP*GP*GP*CP*GP*GP*GP*CP*AP*G)-3') (3 entities in total)
• Functional Keywords: dna polymerase, dna replication, transferase-dna-rna complex, transferase/dna/rna
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Cellular location: Nucleus: P13382
• Total number of polymer chains: 6
• Total formula weight: 223237.94

Authors

Perera, R.L.,Torella, R.,Klinge, S.,Kilkenny, M.L.,Maman, J.D.,Pellegrini, L. (deposition date: 2012-07-03, release date: 2013-02-27, Last modification date: 2023-09-13)

• Primary citation: Perera, R.L.,Torella, R.,Klinge, S.,Kilkenny, M.L.,Maman, J.D.,Pellegrini, L.; Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha; eLife, 2:e00482-, 2013; PubMed: 23599895; DOI: 10.7554/eLife.00482

Experimental method

X-RAY DIFFRACTION (3 Å)