4FVL

Human collagenase 3 (MMP-13) full form with peptides from pro-domain

Summary for 4FVL

Entry DOI	10.2210/pdb4fvl/pdb
Related	1PEX 3TVC 4FU4
Descriptor	Collagenase 3, Collagenase 3, pro-domain peptide, ZINC ION, ... (9 entities in total)
Functional Keywords	protein-peptide complex, collagenase, cleavage with mmp3, hydrolase, pro-peptide, metzincin, zinc metalloprotease, collagen cleavage, collagen
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space, extracellular matrix (Probable): P45452 P45452
Total number of polymer chains	4
Total formula weight	94386.12
Authors	Stura, E.A.,Vera, L.,Visse, R.,Nagase, H.,Dive, V. (deposition date: 2012-06-29, release date: 2013-08-21, Last modification date: 2023-09-13)
Primary citation	Stura, E.A.,Visse, R.,Cuniasse, P.,Dive, V.,Nagase, H. Crystal structure of full-length human collagenase 3 (MMP-13) with peptides in the active site defines exosites in the catalytic domain. Faseb J., 27:4395-4405, 2013 Cited by PubMed: 23913860 DOI: 10.1096/fj.13-233601 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.436 Å)

Structure validation