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4FTV

The complex between the high affinity version of A6 TCR (A6c134) and human Class I MHC HLA-A2 with the bound TAX nonameric peptide

Summary for 4FTV
Entry DOI10.2210/pdb4ftv/pdb
DescriptorHLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Protein Tax-1, ... (7 entities in total)
Functional Keywordstax peptide, nonapeptide, mhc class i, hla-a2, tcr a6, cross-reactivity, high affinity, c134, immune system
Biological sourceHomo sapiens (human)
More
Cellular locationMembrane; Single-pass type I membrane protein: P01892
Secreted: P61769
Host nucleus (By similarity): P0C213
Total number of polymer chains5
Total formula weight95249.41
Authors
Borbulevych, O.Y.,Baker, B.M. (deposition date: 2012-06-28, release date: 2013-07-03)
Primary citationBorbulevych, O.Y.,Baker, B.M.
Structure of a high affinity TCR reveals native binding to MHC with enhanced peptide specificity
To be Published,
Experimental method
X-RAY DIFFRACTION (2.74 Å)
Structure validation

217705

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