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4FL2

Structural and Biophysical Characterization of the Syk Activation Switch

Summary for 4FL2
Entry DOI10.2210/pdb4fl2/pdb
Related4FL1 4FL3
DescriptorTyrosine-protein kinase SYK, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total)
Functional Keywordstransferase, protein kinase
Biological sourceHomo sapiens (human)
Cellular locationCell membrane (Probable): P43405
Total number of polymer chains1
Total formula weight72752.73
Authors
Graedler, U.,Schwarz, D.,Dresing, V.,Musil, M.,Bomke, J.,Frech, M.,Jaekel, S.,Rysiok, T.,Mueller-Pompalla, D.,Wegener, A. (deposition date: 2012-06-14, release date: 2012-11-28, Last modification date: 2024-02-28)
Primary citationGradler, U.,Schwarz, D.,Dresing, V.,Musil, D.,Bomke, J.,Frech, M.,Greiner, H.,Jakel, S.,Rysiok, T.,Muller-Pompalla, D.,Wegener, A.
Structural and biophysical characterization of the syk activation switch.
J.Mol.Biol., 425:309-333, 2013
Cited by
PubMed: 23154170
DOI: 10.1016/j.jmb.2012.11.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.19 Å)
Structure validation

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