4FCI

Crystal Structure of the Mn2+2-Human Arginase I-AGPA Complex

Summary for 4FCI

Entry DOI	10.2210/pdb4fci/pdb
Related	2PHA 4FCK
Descriptor	Arginase-1, MANGANESE (II) ION, 2-AMINO-3-GUANIDINO-PROPIONIC ACID, ... (4 entities in total)
Functional Keywords	arginase fold, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P05089
Total number of polymer chains	2
Total formula weight	69925.66
Authors	D'Antonio, E.L.,Christianson, D.W. (deposition date: 2012-05-25, release date: 2012-06-20, Last modification date: 2023-09-13)
Primary citation	D'Antonio, E.L.,Christianson, D.W. Binding of the unreactive substrate analog L-2-amino-3-guanidinopropionic acid (dinor-L-arginine) to human arginase I. Acta Crystallogr.,Sect.F, 68:889-893, 2012 Cited by PubMed: 22869115 DOI: 10.1107/S1744309112027820 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.82 Å)

Structure validation