4F5I

Substrate Specificity Conversion of E. coli Pyridoxal-5'-Phosphate Dependent Aspartate Aminotransferase to Tyrosine Aminotransferase: Chimera P4.

Summary for 4F5I

Entry DOI	10.2210/pdb4f5i/pdb
Related	4F5F 4F5G 4F5H 4F5J 4F5K 4F5L 4F5M
Descriptor	Aspartate aminotransferase, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
Functional Keywords	aminotransferase, transferase
Biological source	Escherichia coli
Cellular location	Cytoplasm: P00509
Total number of polymer chains	2
Total formula weight	89829.19
Authors	Addington, T.A.,Fisher, A.J.,Toney, M.D. (deposition date: 2012-05-13, release date: 2013-02-13, Last modification date: 2013-04-24)
Primary citation	Addington, T.A.,Mertz, R.W.,Siegel, J.B.,Thompson, J.M.,Fisher, A.J.,Filkov, V.,Fleischman, N.M.,Suen, A.A.,Zhang, C.,Toney, M.D. Janus: prediction and ranking of mutations required for functional interconversion of enzymes. J.Mol.Biol., 425:1378-1389, 2013 Cited by PubMed: 23396064 DOI: 10.1016/j.jmb.2013.01.034 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation