4F3A

Structure of RPE65: P6522 crystal form, iridium derivative

Summary for 4F3A

• Entry DOI: 10.2210/pdb4f3a/pdb
• Related: 3FSN 4F2Z 4F30 4F3D
• Descriptor: Retinoid isomerohydrolase, IRIDIUM (III) ION, FE (II) ION, ... (4 entities in total)
• Functional Keywords: monotopic membrane protein, metalloprotein, non-heme iron protein, beta-propeller, smooth er membrane, isomerase, hydrolase
• Biological source: Bos taurus (bovine)
• Cellular location: Cytoplasm: Q28175
• Total number of polymer chains: 1
• Total formula weight: 61288.26

Authors

Kiser, P.D.,Palczewski, K. (deposition date: 2012-05-09, release date: 2012-10-03, Last modification date: 2024-02-28)

• Primary citation: Kiser, P.D.,Farquhar, E.R.,Shi, W.,Sui, X.,Chance, M.R.,Palczewski, K.; Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis.; Proc.Natl.Acad.Sci.USA, 109:E2747-E2756, 2012; PubMed: 23012475; DOI: 10.1073/pnas.1212025109

Experimental method

X-RAY DIFFRACTION (2.6 Å)